About NCTM
The National Center for Therapeutics Manufacturing (NCTM) is an interdisciplinary workforce education and research center serving the global biopharmaceutical and vaccine manufacturing industries. A member of the Texas A&M Engineering Experiment Station, the NCTM develops and delivers customizable instructor-led, computer-based, and hands-on learning.
Our programs expose students to various aspects of cell culture and basic molecular biology, aseptic processes and microbiology, upstream and downstream processing of biological materials including viruses, mRNA, monoclonal antibodies and other recombinant proteins, as well as industrial bioanalytical methods.
NCTM also provides enabling technologies to academic/medical researchers and start-ups through its blended infrastructure of academic, scientific, and industrial expertise and complete range of bench-to-pilot and Phase I scale bioprocess and analytical equipment.
Our Capabilities
- mRNA production, LNP encapsulation, formulation and QC analysis
- Media screening to improve cell line productivity
- Expression systems including bacteria/yeast/mammalian/algae/insect lines
- Protein expression and purification
- Process development/optimization support
- Analytical methods development and characterization
"It is critical that students and trainees interested in therapeutics and vaccine manufacturing understand the science, technology, and regulatory policy of drug production. NCTM prepares those entering this field and provides opportunities for further professional development."
NCTM2 — Biomanufacturing Training Center, North Texas
3020 Pegasus Park Dr, Dallas, TX 75247
Workforce Development
Located in Pegasus Park's Bridge Labs, NCTM2 serves as the epicenter for biomanufacturing education in North Texas. The 5,000 sq. ft. laboratory features biomanufacturing trainings where participants learn how to produce large molecule medicines through a combination of lectures and hands-on lab activities. NCTM has an extensive course catalog of simulated cGMP manufacturing training and how to operate bioprocessing equipment such as bioreactors, ultrafiltration and chromatography systems. The NCTM catalog also covers other areas including Quality Control and Process Development. The strategic location of NCTM2 allows us to train the North Texas workforce and enhance the local biotech ecosystem.
Research Capabilities
NCTM2 offers research services on a contract basis for a variety of needs. We can produce research grade materials including proteins, cells, plasmids, RNA, and bioindustrial molecules. Our services range from small scale biomass generation to bench scale process scale up studies for efficient means of manufacturing your product. Other services include purification of biomolecules, process development for novel products, and drafting of documents including SOPs and BPRs. NCTM2 can also perform analysis of products for concentration, identity, and purity.
Collaboration with UTA IMPRINT
NCTM2 is co-operated by the Texas A&M NCTM team and UTA IMPRINT. One of IMPRINT's initiatives involves contract training of our Biopharma Bootcamp course to train UTA Biomedical Engineering majors on the biomanufacturing of large molecule drugs such as insulin and monoclonal antibodies. This is a 5-day short course slotted around the standard academic semesters where students get the opportunity to produce and purify a model recombinant protein in E. coli through the operation of bioreactors, ultrafiltration systems, chromatography systems, and more.
The experience is a combination of lectures and hands-on lab activities designed to expose students to the breadth of products, unit operations, equipment, and requirements in the growing biomanufacturing industry. This experience culminates in a certificate of completion, digital badges, and a host of knowledge and experience to differentiate participants from peers who don't have hands-on experience and deeper knowledge.
About IMPRINT
Aligned with The University of Texas at Arlington's mission to advance knowledge through scholarship and creative work, the Institute of Biomanufacturing and Precision Medicine for North Texas (IMPRINT) works with strategic industry partners to drive economic growth, address unmet medical needs, expand UTA's life and health sciences research, and enhance student experiential learning.